Jurgen Klopp is “full of confidence and trust” in Nathaniel Phillips as the center-half has been given a rare start at Brighton.
The 23-year-old saw Liverpool come out of West Ham earlier this season and played at the heart of the defense.
He will be partnering with incumbent defender Fabinho as he embarks on his second Premier League debut.
Klopp admits he tries and demands continuity along his defensive line but the nature of the situation makes it difficult.
He said: “Again (another center-half pair). It works. They did really well against West Ham and Nat is a super boy.
“I don’t like constantly changing the last line but on the other hand he has to get a chance.
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“I have full faith and confidence in him, and he will give me everything I have.
Takumi Minamino has also been given a rare start from the start as he took advantage of an innings by Curtis Jones.
“You need fresh legs,” Klopp continued.
“Curtis told me yesterday that he felt something and he couldn’t train but is on the bench.
“So it was clear we needed another midfielder so I thought I’d bring Takumi in.”
The Germans have regularly lamented the workload on their players as the fixtures are dense and fast.
Liverpool are playing their third game in seven days and will host Merseyside and Ajax in just 72 hours.
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Sadio Mane has been rested and there is a significant reduction in the members of the Senegalese Star.
They travel to the South Coast where they aim to pick up three points against the lower Seagulls, although Klopp claims they are far better than their league position suggestions.
The Germans saw their side lose at midweek in the Champions League against the Italian team Atalanta.
Last weekend, however, they looked comfortable with Leicester 3-0 at Anfield as they made fun of their absent list.
Liverpool can top with a point at the Amex Stadium, with Tottenham playing Chelsea on Sunday for at least 24 hours.
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